SYNTHESIS, ANTIMICROBIAL EVALUATION, DENSITY FUNCTIONAL THEORY, AND DOCKING STUDIES OF SOME NEW 2-MERCAPTO PYRIMIDINE SCHIFF BASES
نویسندگان
چکیده
منابع مشابه
synthesis and characterization of some macrocyclic schiff bases
ماکروسیکلهای شیف باز از اهمیت زیادی در شیمی آلی و دارویی برخوردار می باشند. این ماکروسیکلها با دارابودن گروه های مناسب در مکانهای مناسب می توانند فلزاتی مثل مس، نیکل و ... را در حفره های خود به دام انداخته، کمپلکسهای پایدار تولید نمایند. در این پایان نامه ابتدا یک دی آلدئید آروماتیک از گلیسیرین تهیه می شود و در مرحله بعدی واکنش با دی آمینهای آروماتیک و یا آلیفاتیک در رقتهای بسیار زیاد منجر به ت...
15 صفحه اولSynthesis and Antibacterial Evaluation of New Thione Substituted 1,2,4-Triazole Schiff Bases as Novel Antimicrobial Agents
The condensation reaction of 5-(4-aminophenyl)-4-phenyl-1,2,4-triazole-3-thione with salicylaldehyde, 4-hydroxybenzaldehyde, 5-chlorosalicylaldehyde, 5-bromosalicylaldehyde, 2-nitrobenzaldehyde, 3-nitrobenzaldehyde, 4-nitrobenzaldehyde and 4-methoxybenzaldehyde in methanol results in series of new Schiff bases. The structure of Schiff bases were confirmed by 1H NMR, 13C NMR, IR and mass spectro...
متن کاملSynthesis and Antibacterial Evaluation of New Thione Substituted 1,2,4-Triazole Schiff Bases as Novel Antimicrobial Agents
The condensation reaction of 5-(4-aminophenyl)-4-phenyl-1,2,4-triazole-3-thione with salicylaldehyde, 4-hydroxybenzaldehyde, 5-chlorosalicylaldehyde, 5-bromosalicylaldehyde, 2-nitrobenzaldehyde, 3-nitrobenzaldehyde, 4-nitrobenzaldehyde and 4-methoxybenzaldehyde in methanol results in series of new Schiff bases. The structure of Schiff bases were confirmed by 1H NMR, 13C NMR, IR and mass spectro...
متن کاملSYNTHESIS, CHARACTERIZATION, ANTIMICROBIAL ACTIVITIES AND DNA– BINDING STUDIES OF SOME Ru (III) COMPLEXES OF SCHIFF BASES
A new ruthenium (III) Schiff base complexes of the type [RuX2 (PPh3)2(L)] (where X = Cl or Br; L = monobasic bidentate Ligand) have been synthesized. All the complexes were characterized by analytical, IR, electronic and EPR spectral studies. An octahedral geometry has been tentatively proposed to all the new complexes. Further the ligands and complexes were subjected to antimicrobial activity ...
متن کاملDesign and synthesis of new symmetrical Schiff bases
A series of symmetric multidentate Schiff base ligands 1–13 based on the N‚N′-4‚4′-ethylenebiphenylbis-3-methoxysalicylideneimine for used to bind various transition metals detection of K, AgI‚ CuII, Sr II Co II and NiII at trace levels in real-world samples has been synthesized purified and their structures was characterized.
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ژورنال
عنوان ژورنال: Asian Journal of Pharmaceutical and Clinical Research
سال: 2019
ISSN: 2455-3891,0974-2441
DOI: 10.22159/ajpcr.2019.v12i2.30858